Cystinosis

Active Ingredient: Mercaptamine

Indication for Mercaptamine

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Mercaptamine is indicated for the treatment of corneal cystine crystal deposits in adults and children from 2 years of age with cystinosis.

For this indication, competent medicine agencies globally authorize below treatments:

4 drops in 4 divided doses daily

Route of admnistration

Ophthalmic

Defined daily dose

4 - 4 {drops}

Dosage regimen

From 1 To 1 {drops} 4 time(s) per day every day

Detailed description

The recommended dose is one drop in each eye, 4 times a day during waking hours. The recommended interval between each instillation is 4 hours. The dose could be decreased progressively (to a minimum total daily dose of 1 drop in each eye) depending on the results of ophthalmic examination (such as, corneal cystine crystal deposits, photophobia).

If the patient misses an instillation, the patient should be told to continue the treatment with the next instillation.

The dose should not exceed 4 drops a day in each eye.

The accumulation of corneal cystine crystals increases if mercaptamine is discontinued. The treatment should not be stopped.

Paediatric population

Mercaptamine may be used in paediatric patients from 2 years of age at the same dose as in adults.

The safety and efficacy of mercaptamine in children aged less than 2 years has not been established. No data are available.

Active ingredient

Mercaptamine

Mercaptamine reduces corneal cystine crystal accumulation acting as a cystine-depleting agent by converting cystine to cysteine and cysteine-cysteamine mixed disulfides.

Read more about Mercaptamine

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