HIV-1 infection

Active Ingredient: Maraviroc

Indication for Maraviroc

Population group: only adults (18 - 65 years old)

Maraviroc, in combination with other antiretroviral medicinal products, is indicated for treatment-experienced adults, adolescents and children of 2 years of age, and older and weighing at least 10 kg infected with only CCR5-tropic HIV-1 detectable.

For this indication, competent medicine agencies globally authorize below treatments:

300-1200 mg in 2 divided doses daily

Route of admnistration


Defined daily dose

300 - 1,200 mg

Dosage regimen

From 150 To 600 mg 2 time(s) per day every day

Detailed description

The recommended dose of maraviroc is 150 mg (with potent CYP3A inhibitor with or without a potent CYP3A inducer), 300 mg (without potent CYP3A inhibitors or inducers) or 600 mg twice daily (with potent CYP3A inducer without a potent CYP3A inhibitor) depending on interactions with concomitant antiretroviral therapy and other medicinal products.

Dosage considerations

Maraviroc can be taken with or without food.

Active ingredient


Maraviroc is a member of a therapeutic class called CCR5 antagonists. Maraviroc selectively binds to the human chemokine receptor CCR5, preventing CCR5-tropic HIV-1 from entering cells.

Read more about Maraviroc

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