Bronchial asthma

Active Ingredient: Cromoglicic acid

Indication for Cromoglicic acid

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Cromoglicic acid is indicated for the preventative treatment of bronchial asthma, in adults and children.

For this indication, competent medicine agencies globally authorize below treatments:

20-80 mg in 4 divided doses daily

Route of admnistration

Respiratory (Inhalation)

Defined daily dose

20 - 80 mg

Dosage regimen

From 5 To 20 mg 4 time(s) per day every day

Loading dose

40 mg

Detailed description

The initial dose is 10mg of the aerosol four times daily. Once adequate control of symptoms has been achieved it may be possible to reduce to a maintenance dose of 5mg inhalation four times daily. However, the dose may be increased to 10mg six or eight times daily in more severe cases or during periods of severe antigen challenge. An additional dose before exercise may also be taken.

Concomitant Bronchodilator Therapy

Where a concomitant aerosol bronchodilator is prescribed it is recommended that this be administered prior to sodium cromoglicate.

Concomitant Steroid Therapy

In patients currently treated with steroids, the addition of sodium cromoglicate to the regimen may make it possible to reduce the maintenance dose of steroids, or discontinue steroid therapy completely. The patient must be carefully supervised while the steroid dose is reduced; a rate of 10% weekly is suggested.

If reduction of a steroid dosage has been possible, sodium cromoglicate should not be withdrawn until steroid cover has been reinstituted.

Active ingredient

Cromoglicic acid

Sodium cromoglicate (Cromoglicic acid) inhibits the activation of many of the cell types involved in the development and progression of asthma. Thus, sodium cromoglicate inhibits the release of inflammatory mediators including cytokines from mast cells and reduces the chemotactic activity of eosinophils and neutrophils.

Read more about Cromoglicic acid

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