Bowel clearance before surgery

Active Ingredient: Bisacodyl

Indication for Bisacodyl

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Bowel clearance before surgery or radiological investigation. Replacement of the evacuant enema in all its indications.

For this indication, competent medicine agencies globally authorize below treatments:

10-30 mg daily

Route of admnistration

Oral

Defined daily dose

10 - 30 mg

Dosage regimen

From 10 To 30 mg once every day for 1 day(s)

Detailed description

It should be administered under medical supervision during pre-diagnostic, pre-and post-operative treatment and generally in medical conditions requiring bowel evacuation.

To achieve complete bowel emptying, its recommended dosage for adults is 10-20mg orally in the evening before the test, followed by 10mg rectally in the morning of the test.

Active ingredient

Bisacodyl

Bisacodyl is a locally acting laxative from the diphenylmethane derivatives group having a dual action. As a contact laxative, for which also antiresorptive hydragogue effects have been described, bisacodyl stimulates after hydrolysis in the large intestine, the mucosa of both the large intestine and of the rectum. Stimulation of the mucosa of the large intestine results in colonic peristalsis with promotion of accumulation of water, and consequently electrolytes, in the colonic lumen. This results in a stimulation of defecation, reduction of transit time and softening of the stool. Stimulation of the rectum causes increased motility and a feeling of rectal fullness. The rectal effect may help to restore the “call to stool” although its clinical relevance remains to be established.

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