Active Ingredient: Enoxaparin
Acute coronary syndrome:
Treatment of unstable angina and Non ST-segment elevation myocardial infarction (NSTEMI), in combination with oral acetylsalicylic acid.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Regimen A
Subcutaneous, 100 international units enoxaparin per kilogram of body weight, once every 12 hours, over the duration of 2 to 8 days.
Regimen B
Subcutaneous, 1 milligrams enoxaparin per kilogram of body weight, once every 12 hours, over the duration of 2 to 8 days.
For treatment of unstable angina and NSTEMI, the recommended dose of enoxaparin sodium is 100 IU/kg (1 mg/kg) every 12 hours by SC injection administered in combination with antiplatelet therapy. Treatment should be maintained for a minimum of 2 days and continued until clinical stabilization. The usual duration of treatment is 2 to 8 days.
Acetylsalicylic acid is recommended for all patients without contraindications at an initial oral loading dose of 150–300 mg (in acetylsalicylic acid-naive patients) and a maintenance dose of 75–325 mg/day long-term regardless of treatment strategy.
Injection should be made preferably when the patient is lying down. Enoxaparin sodium is administered by deep SC injection.
The administration should be alternated between the left and right anterolateral or posterolateral abdominal wall.
The whole length of the needle should be introduced vertically into a skin fold gently held between the thumb and index finger. The skin fold should not be released until the injection is complete. After administration, the injection site should not be rubbed.
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