Active Ingredient: Bendamustine
Front line treatment of multiple myeloma (Durie-Salmon stage II with progress or stage III) in combination with prednisone for patients older than 65 years who are not eligible for autologous stem cell transplantation and who have clinical neuropathy at time of diagnosis precluding the use of thalidomide or bortezomib containing treatment.
For this indication, competent medicine agencies globally authorize below treatments:
Intravenous
120 - 150 mg per m² of body surface area (BSA)
From 120 To 150 mg per m² of body surface area (BSA) once every day for 2 day(s)
120-150 mg/m² body surface area bendamustine hydrochloride on days 1 and 2, 60 mg/m² body surface area prednisone i.v. or per os on days 1 to 4; every 4 weeks for at least 3 times.
For intravenous infusion over 30-60 min.
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