Parkinson's disease

Active Ingredient: Selegiline

Indication for Selegiline

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

Selegiline is indicated for the treatment of Parkinson’s disease, or symptomatic parkinsonism. It may be used alone in early Parkinson’s disease for symptomatic relief to delay the need for levodopa (with or without decarboxylase inhibitor).

For this indication, competent medicine agencies globally authorize below treatments:

10 mg daily

For:

Dosage regimens

Regimen A: Oral, 10 milligrams selegiline, once daily at morning.

Regimen B: Oral, 5 milligrams selegiline, 2 times daily to meals.

Detailed description

Selegiline may be administered either as a single dose in the morning or in two divided doses of 5 mg, taken at breakfast and lunch.

Active ingredient

Selegiline

Selegiline is a selective MAO-B-inhibitor which prevents dopamine breakdown in the brain. It also inhibits the reuptake of dopamine at the presynaptic dopamine receptor. These effects potentiate dopaminergic function in the brain and help to even out and prolong the effect of exogenous and endogenous dopamine. Thus, selegiline potentiates and prolongs the effect of levodopa in the treatment of parkinsonism.

Read more about Selegiline

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