Active Ingredient: Cemiplimab
Cemiplimab as monotherapy is indicated for the adjuvant treatment of adult patients with CSCC at high risk of recurrence after surgery and radiation.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Regimen A
Intravenous, 350 milligrams cemiplimab, once every 3 weeks, over the duration of 12 weeks. Afterwards, intravenous, 700 milligrams cemiplimab, once every 6 weeks, over the duration of up to 36 weeks.
Regimen B
Intravenous, 350 milligrams cemiplimab, once every 3 weeks, over the duration of up to 48 weeks.
The recommended dose of cemiplimab administered as an intravenous infusion over 30 minutes is:
Treatment may be continued until disease recurrence, unacceptable toxicity, or up to 48 weeks of total therapy.
No dose adjustment is recommended for elderly patients. Cemiplimab exposure is similar across all age groups. Data are limited in patients ≥75 years on cemiplimab monotherapy.
Cemiplimab is administered by intravenous infusion over 30 minutes through an intravenous line containing a sterile, non-pyrogenic, low-protein binding, in-line or add-on filter (0.2 micron to 5 micron pore size).
Other medicinal products should not be co-administered through the same infusion line.
Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.