Sedation during minor medical procedures

Active Ingredient: Midazolam

Indication for Midazolam

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Midazolam is indicated in children from 6 months to 17 years old, for moderate sedation before a therapeutic or diagnostic procedure.

For this indication, competent medicine agencies globally authorize below treatments:

0.25 mg/kg

Route of admnistration

Oral

Defined daily dose

0.25 - 0.25 mg per kg of body weight

Dosage regimen

From 0.25 To 0.25 mg per kg of body weight once every day

Detailed description

The dose must be adapted to the patient’s weight.

Midazolam should be used orally at a single dose of 0.25 mg/kg in children from the age of six months.

The maximum dose should not exceed 20 mg of midazolam (corresponding to 2 ampoules), even for children weighing more than 80 kg.

In obese children the dose should be given according to actual body weight, up to the limit of 20 mg.

Dosage considerations

Midazolam should be administered on average 30 minutes before the procedure.

Active ingredient

Midazolam

Midazolam is a derivative of the imidazobenzodiazepine group. The free base is a lipophilic substance with low solubility in water. The basic nitrogen in position 2 of the imidazobenzodiazepine ring system enables the active ingredient of midazolam to form water-soluble salts with acids.

Read more about Midazolam

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