For this indication, competent medicine agencies globally authorize below treatments:
4,000,000 - 5,000,000 [iU]
From 4,000,000 To 5,000,000 [iU] once every day
The recommended dose of interferon alpha-2b is 4 to 5 million IU/m² administered daily subcutaneously. Some patients have been shown to benefit from interferon alpha-2b 5 million IU/m² administered daily subcutaneously in association with cytarabine (Ara-C) 20 mg/m² administered daily subcutaneously for 10 days per month (up to a maximum daily dose of 40 mg). When the white blood cell count is controlled, administer the maximum tolerated dose of interferon alpha-2b (4 to 5 million IU/m² daily) to maintain haematological remission.
Interferon alpha-2b treatment must be discontinued after 8 to 12 weeks of treatment if at least a partial haematological remission or a clinically meaningful cytoreduction has not been achieved.
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