Active Ingredient: Fluorouracil
Fluorouracil is used for the topical treatment of superficial pre-malignant and malignant skin lesions; keratoses including senile, actinic and arsenical forms; keratoacanthoma; Bowen’s disease; superficial basal-cell carcinoma. Deep, penetrating or nodular basal cell and squamous cell carcinomas do not usually respond to fluorouracil therapy. It should be used only as a palliative therapy in such cases where no other form of treatment is possible.
For this indication, competent medicine agencies globally authorize below treatments:
Cutaneous
2 - 2 {dose}
From 1 To 1 {dose} 2 time(s) per day every day
Pre-malignant conditions: The cream should be applied thinly to the affected area once or twice daily; an occlusive dressing is not essential.
Malignant conditions: The cream should be applied once or twice daily under an occlusive dressing where this is practicable.
The cream should not harm healthy skin. Treatment should be continued until there is marked inflammatory response from the treated area, preferably with some erosion in the case of pre-malignant conditions. Severe discomfort may be alleviated by the use of topical steroid cream. The usual duration of treatment for an initial course of therapy is three to four weeks, but this may be prolonged. Lesions on the face usually respond more quickly than those on the trunk or lower limbs whilst lesions on the hands and forearms respond more slowly. Healing may not be complete until one or two months after therapy is stopped.
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