Rheumatoid arthritis (RA)

Active Ingredient: Anakinra

Indication for Anakinra

Population group: only adults (18 years old or older)

Anakinra is indicated in adults for the treatment of the signs and symptoms of RA in combination with methotrexate, with an inadequate response to methotrexate alone.

For this indication, competent medicine agencies globally authorize below treatments:

100 mg once a day

Route of admnistration


Defined daily dose

100 - 100 mg

Dosage regimen

From 100 To 100 mg once every day

Detailed description

The recommended dose of anakinra is 100 mg administered once a day by subcutaneous injection. The dose should be administered at approximately the same time each day.

Active ingredient


Anakinra neutralises the biologic activity of interleukin-1α (IL-1α) and interleukin-1β (IL-1β) by competitively inhibiting their binding to interleukin-1 type I receptor (IL-1RI). Interleukin-1 (IL-1) is a pivotal pro-inflammatory cytokine mediating many cellular responses including those important in synovial inflammation.

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