Prader-Willi syndrome (PWS)

Active Ingredient: Somatropin

Indication for Somatropin

Population group: only minors (0 - 18 years old)
Therapeutic intent: Curative procedure

Prader-Willi syndrome (PWS), for improvement of growth and body composition. The diagnosis of PWS should be confirmed by appropriate genetic testing.

For this indication, competent medicine agencies globally authorize below treatments:

35 ug/kg once daily

For:

Route of admnistration

Subcutaneous

Defined daily dose

35 - 35 ug per kg of body weight

Dosage regimen

From 35 To 35 ug per kg of body weight once every day

Detailed description

Generally a dose of 0.035 mg/kg body weight per day is recommended. Daily doses of 2.7 mg should not be exceeded. Treatment should not be used in children with a growth velocity of less than 1 cm per year and near closure of epiphyses.

Dosage considerations

The injection should be given subcutaneously and the site varied to prevent lipoatrophy.

1.0 mg/m² once daily

For:

Route of admnistration

Subcutaneous

Defined daily dose

1 - 1 mg per m² of body surface area (BSA)

Dosage regimen

From 1 To 1 mg per m² of body surface area (BSA) once every day

Detailed description

Generally a dose of 1.0 mg/m² body surface area per day is recommended. Daily doses of 2.7 mg should not be exceeded. Treatment should not be used in children with a growth velocity of less than 1 cm per year and near closure of epiphyses.

Dosage considerations

The injection should be given subcutaneously and the site varied to prevent lipoatrophy.

Active ingredient

Somatropin

Somatropin is a potent metabolic hormone of importance for the metabolism of lipids, carbohydrates and proteins. In children with inadequate endogenous growth hormone, somatropin stimulates linear growth and increases growth rate. In adults, as well as in children, somatropin maintains a normal body composition by increasing nitrogen retention and stimulation of skeletal muscle growth, and by mobilization of body fat.

Read more about Somatropin

Related medicines

Develop a tailored medication plan for your case, considering factors such as age, gender, and health history

Ask the Reasoner

Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.