Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2019 Publisher: Accord-UK Ltd (Trading style: Accord), Whiddon Valley, Barnstaple, Devon, EX32 8NS
VERAPAMIL TABLETS BP 40mg.
Pharmaceutical Form |
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Yellow film-coated tablets. Yellow, circular, biconvex film-coated tablets, impressed “C” on one face and the identifying letters “VR” on the reverse. Tablet diameter: 6.18-6.82mm. |
Each tablet contains 40mg Verapamil Hydrochloride PhEur.
Excipient with known effect: Sunset yellow aluminium lake (E110).
For the full list of excipients, see section 6.1.
Active Ingredient | Description | |
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Verapamil |
Verapamil is a phenylalkylamine calcium antagonist which blocks the inward movement of calcium ions in cardiac muscle cells, in smooth muscle cells of the coronary and systemic arteries and in cells of the intracardiac conduction system. It lowers heart rate, increases myocardial perfusion and reduces coronary spasm. Because of its effect on the movement of calcium in the intracardiac conduction system, verapamil reduces automaticity, decreases conduction velocity and increases the refractory period. |
List of Excipients |
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Also contains: Croscarmellose sodium |
The product containers are rigid injection moulded polypropylene or injection blow-moulded polyethylene containers and snap-on polyethylene lids; in case any supply difficulties should arise the alternative is amber glass containers with screw caps.
The product may also be supplied in blister packs and cartons:
Pack size: 28s, 30s, 56s, 60s, 84s, 90s, 100s, 112s, 120s, 168s, 180s, 250s, 500s, 1000s.
Product may also be supplied in bulk packs, for reassembly purposes only, in polybags contained in tins, skillets or polybuckets filled with suitable cushioning material. Bulk packs are included for temporary storage of the finished product before final packaging into the proposed marketing containers.
Maximum size of bulk packs: 50,000.
Accord-UK Ltd (Trading style: Accord), Whiddon Valley, Barnstaple, Devon, EX32 8NS
PL 0142/0281
Date of first authorisation: 18th September 1989
Date of latest renewal: 7th July 1997
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