HYPNOMIDATE Solution for injection Ref.[9262] Active ingredients: Etomidate

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2018  Publisher: Piramal Critical Care Limited, Suite 4, Ground Floor, Heathrow Boulevard East Wing, 280 Bath Road, West Drayton, UB7 0DQ, United Kingdom, Tel: 00441670562400

Product name and form

Hypnomidate 2 mg/ml Injection.

Pharmaceutical Form

Solution for injection.

Qualitative and quantitative composition

Each ml of Hypnomidate contains etomidate 2 mg.

Active Ingredient Description
Etomidate

Etomidate is an imidazole derivative with short-acting sedative, hypnotic, and general anesthetic properties. Etomidate appears to have gamma-aminobutyric acid (GABA) like effects, mediated through GABA-A receptor. The action enhances the inhibitory effect of GABA on the central nervous system by causing chloride channel opening events which leads to membrane hyperpolarization.

List of Excipients

Propylene glycol
Water for injections
1N sodium hydroxide*
1N hydrochloric acid*

* for occasional pH adjustment only

Pack sizes and marketing

Colourless glass ampoule, Ph.Eur. Type I, containing 10 ml Hypnomidate, in packs of 5 and 10 ampoules.

Not all pack sizes may be marketed.

Marketing authorization holder

Piramal Critical Care Limited, Suite 4, Ground Floor, Heathrow Boulevard – East Wing, 280 Bath Road, West Drayton, UB7 0DQ, United Kingdom, Tel: 00441670562400

Marketing authorization dates and numbers

PL 37071/0006

27 October 1978/20 March 2004

Drugs

Drug Countries
HYPNOMIDATE Austria, Brazil, Estonia, Spain, France, Croatia, Malta, Netherlands, Poland, Tunisia, United Kingdom, South Africa

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