REBIF

This brand name is authorized in Nigeria. It is also authorized in Australia, Austria, Brazil, Canada, Croatia, Cyprus, Ecuador, Estonia, Finland, France, Hong Kong SAR China, Ireland, Israel, Italy, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, South Africa, Spain, Tunisia, Turkey, UK, United States.

Active ingredients

The drug REBIF contains one active pharmaceutical ingredient (API):

1	Interferon beta-1a UNII XRO4566Q4R - INTERFERON BETA-1A
	Interferon beta-1a exerts its biological effects by binding to specific receptors on the surface of human cells. This binding initiates a complex cascade of intracellular events that leads to the expression of numerous interferon-induced gene products and markers. Whether the mechanism of action of interferon beta-1a in MS is mediated by the same pathway as the biological effects described above is not known because the pathophysiology of MS is not well established.
	Read more about Interferon beta-1a

Packages

This drug has been approved in Nigeria as follows:

Identifier	Form	Presentation	Description	Approval
A6-100135	Solution for injection	REBIF 44 MICROGRAMS SOLUTION FOR INJECTION INJ_SOL 44 mcg/ 0.5 mL 0.5mL X 12 Pre-filled syringes	3 mL pre-filled Type I glass cartridge (with net content of 0.5 mL) (Box of 12's)	05/11/2023

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
L03AB07	Interferon beta-1a	L Antineoplastic and immunomodulating agents → L03 Immunostimulants → L03A Immunostimulants → L03AB Interferons
Discover more medicines within L03AB07

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
AU	Pharmaceutical Benefits Scheme	8403G, 8968B, 9332E
BR	Câmara de Regulação do Mercado de Medicamentos	525420401153414, 525420402151415
CA	Health Products and Food Branch	02237319, 02237320, 02318253, 02318261
EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	26.640-10-05
EE	Ravimiamet	1010866, 1035931, 1071638, 1071683, 1117639, 1117640, 1226607, 1430660, 1430671, 1489147, 1489158, 1489169, 1489305, 1489316, 1489327, 1489338, 1489349, 1646704, 1646715, 1778508, 1778519
ES	Centro de información online de medicamentos de la AEMPS	98063008, 98063009, 98063009IP
FI	Lääkealan turvallisuus- ja kehittämiskeskus	032660, 034977, 034988, 036108, 059873, 151341, 156713, 169894, 518977
FR	Base de données publique des médicaments	62090595, 62332372, 62657978, 63866728, 66975533, 68319944, 68975699, 69483042
GB	Medicines & Healthcare Products Regulatory Agency	113916, 114131, 114155, 166030, 166033, 166369, 186508, 186511, 186516, 186518, 186524, 44036, 44068
HK	Department of Health Drug Office	57955, 57957, 59718, 59719, 62254, 62255
IE	Health Products Regulatory Authority	88291, 88292, 88367, 88368, 88369, 88556, 88834
IL	מִשְׂרַד הַבְּרִיאוּת	6117, 6118
IT	Agenzia del Farmaco	034091013, 034091025, 034091037, 034091049, 034091052, 034091064, 034091076, 034091088, 034091090, 034091102, 034091114, 034091126, 034091138, 034091140, 034091153, 034091165, 034091177, 034091203, 034091215
LT	Valstybinė vaistų kontrolės tarnyba	1004423, 1005538, 1006944, 1006945, 1015559, 1015560, 1030645, 1036693, 1064264, 1071810, 1084982, 1084983, 1091260, 1091261, 1091262, 1091263, 1091264, 1091265, 1091266, 1091267, 1091268
NG	Registered Drug Product Database	A6-100135
NL	Z-Index G-Standaard	14229897
NL	Z-Index G-Standaard, PRK	100021, 100056, 100064, 100072, 100080, 100196
NZ	Medicines and Medical Devices Safety Authority	20695, 20696, 8897, 8898
PL	Rejestru Produktów Leczniczych	100085051, 100101666, 100159217, 100402439, 100402445
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W65162001, W65162002, W65162003, W65163001, W65163002, W65164001, W65164002, W65164003, W65165001
SG	Health Sciences Authority	13974P, 13975P, 14524P, 14525P
TN	Direction de la Pharmacie et du Médicament	22073031H, 22073032H, 22073033H, 22073034H, 6363054H, 6363055H
TR	İlaç ve Tıbbi Cihaz Kurumu	8699777950186, 8699777950209, 8699777950216, 8699777950353, 8699777950360, 8699777950377, 8699777950384
US	FDA, National Drug Code	44087-0022, 44087-0044, 44087-3322, 44087-3344
ZA	Health Products Regulatory Authority	34/34/0096, 35/34/0188, 45/34/1025, 45/34/1026