Anatomical Therapeutic Chemical Classification System
Ispaghula is particularly rich in alimentary fibres and mucilages. Ispaghula is capable of absorbing up to 40 times its own weight in water. Gut motility and transit rate can be modified by ispaghula through mechanical stimulation of the gut wall as a result of the increase in intestinal bulk by water and the decrease in viscosity of the luminal contents.
Methylcellulose is a chemical compound derived from cellulose. Methylcellulose is used to treat constipation. It is classified as a bulk forming laxative. Methylcellulose is a hydrophilic colloid which absorbs water causing it to swell to a soft gel of uniform consistency. It works by increasing the amount of stool present which improves intestinal contractions.