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ATC Group: A06AG Enemas

Anatomical Therapeutic Chemical Classification System

Hierarchical Position

Level
Code
Title
1
A
Alimentary tract and metabolism
2
A06
Laxatives
3
A06A
Laxatives
4
A06AG
Enemas

Contents

Code
Title
A06AG01
Sodium phosphate
A06AG02
Bisacodyl
A06AG03
Dantron, incl. combinations
A06AG04
Glycerol
A06AG06
Oil
A06AG07
Sorbitol
A06AG10
Docusate sodium, incl. combinations
A06AG11
Sodium lauryl sulfoacetate, incl. combinations
A06AG20
Combinations

Active Ingredients

Chemical substance
Description
Bisacodyl

Bisacodyl is a locally acting laxative from the diphenylmethane derivatives group having a dual action. As a contact laxative, for which also antiresorptive hydragogue effects have been described, bisacodyl stimulates after hydrolysis in the large intestine, the mucosa of both the large intestine and of the rectum. Stimulation of the mucosa of the large intestine results in colonic peristalsis with promotion of accumulation of water, and consequently electrolytes, in the colonic lumen. This results in a stimulation of defecation, reduction of transit time and softening of the stool. Stimulation of the rectum causes increased motility and a feeling of rectal fullness. The rectal effect may help to restore the “call to stool” although its clinical relevance remains to be established.

Glycerol

Glycerol has uses as a hyperosmotic, osmotic diuretic, and ophthalmic agent. It may be used as an eye drop in the treatment of glaucoma to reduce intraocular pressure, as a solution or suppository for short-term treatment of constipation, to evacuate the bowel prior to a colonoscopy, and in some ocular surgeries. It may be given intravenously to reduce pressure inside the brain and used externally on the skin as a moisturizer.

Sodium dihydrogen phosphate dihydrate
Sodium lauryl sulphoacetate
Sodium phosphate
Disodium phosphate
Monosodium phosphate
Sorbitol

Monographs

Monograph
Type
Country
GLYCERIN BP Liquid
MPI, EU: SmPC
UK
GLYCERIN Suppository
MPI, EU: SmPC
UK
NORGALAX Rectal gel
MPI, EU: SmPC
UK