ATC Group: A10BF Alpha glucosidase inhibitors

Acarbose is an alpha-glucosidase inhibitors, used in the treatment of diabetes. Inhibitors of a-glucosidase retard the breakdown of carbohydrates in the food and reduce the increase in blood glucose levels, which occurs after each meal.

Miglitol is a reversible inhibitor of intestinal alpha-glucosidases. Under the influence of miglitol, the digestion of complex carbohydrates into absorbable monosaccharides in the small intestine is dosedependently delayed. Administration of miglitol thus leads to reduced postprandial hyperglycaemia and a smoothing effect on fluctuations in the daily blood glucose profile.