ATC Group: C02KN Other antihypertensives

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of C02KN in the ATC hierarchy

Level Code Title
1 C Cardiovascular system
2 C02 Antihypertensives
3 C02K Other antihypertensives
4 C02KN Other antihypertensives

Group C02KN contents

Code Title
C02KN01

Active ingredients in C02KN

Active Ingredient

Endothelin (ET)-1, via its receptors (ETA and ETB), mediates a variety of effects such as vasoconstriction, fibrosis, cell proliferation, and inflammation and is upregulated in hypertension. Aprocitentan is a dual ERA that inhibits the binding of ET-1 to ETA and ETB receptors and hence the effects mediated by these receptors.

Related product monographs

Document Type Information Source  
 JERAYGO Film-coated tablet MPI, EU: SmPC European Medicines Agency (EU)
 TRYVIO Film-coated tablet MPI, US: SPL/PLR FDA, National Drug Code (US)
Go to ATC index
⇈