The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
Level | Code | Title | |
---|---|---|---|
1 | C | Cardiovascular system | |
2 | C08 | Calcium channel blockers | |
3 | C08D | Selective calcium channel blockers with direct cardiac effects |
Code | Title | |
---|---|---|
C08DA | Phenylalkylamine derivatives | |
C08DB | Benzothiazepine derivatives |
Active Ingredient | Description | |
---|---|---|
Diltiazem |
Diltiazem is a calcium antagonist. It restricts the slow channel entry of calcium into the cell and so reduces the liberation of calcium from stores in the sarcoplasmic reticulum. This results in a reduction of the amount of available intracellular calcium reducing myocardial oxygen consumption. |
|
Verapamil |
Verapamil is a phenylalkylamine calcium antagonist which blocks the inward movement of calcium ions in cardiac muscle cells, in smooth muscle cells of the coronary and systemic arteries and in cells of the intracardiac conduction system. It lowers heart rate, increases myocardial perfusion and reduces coronary spasm. Because of its effect on the movement of calcium in the intracardiac conduction system, verapamil reduces automaticity, decreases conduction velocity and increases the refractory period. |
Title | Information Source | Document Type | |
---|---|---|---|
ADIZEM-XL Prolonged release capsule | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
AKILEN Film-coated tablet | Υπουργείο Υγείας (CY) | MPI, EU: SmPC | |
CARDIZEM CD Extended-release capsule | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
ISOPTIN Film‐coated tablet | Health Products Regulatory Authority (IE) | MPI, EU: SmPC | |
ISOPTIN Solution for injection / infusion | Health Products Regulatory Authority (IE) | MPI, EU: SmPC | |
SECURON Solution for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
SECURON SR Modified-release tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
TIAZAC Capsule, ectended release | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
TILDIEM Modified-release tablets | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
VERAPAMIL Film-coated tablets | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |