ATC Group: H02C Antiadrenal preparations

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of H02C in the ATC hierarchy

Level Code Title
1 H Systemic hormonal preparations, excl. Sex hormones and insulins
2 H02 Corticosteroids for systemic use
3 H02C Antiadrenal preparations

Group H02C contents

Code Title
H02CA Anticorticosteroids

Active ingredients in H02C

Active Ingredient Description
Ketoconazole

Ketoconazole is an imidazole-dioxolane antimycotic, active against yeasts, including Malassezia and dermatophytes.

Osilodrostat

Osilodrostat is a cortisol synthesis inhibitor. It potently inhibits 11β-hydroxylase (CYP11B1), the enzyme responsible for the final step of cortisol biosynthesis in the adrenal gland. In Cushing’s disease, the fall in plasma cortisol concentration also stimulates ACTH secretion, via the feedback mechanism which accelerates steroid biosynthesis.

Trilostane

Related product monographs

Title Information Source Document Type  
ISTURISA Film-coated tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
ISTURISA Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC