ATC Group: L04AJ05 Avacopan

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of L04AJ05 in the ATC hierarchy

Level Code Title
1 L Antineoplastic and immunomodulating agents
2 L04 Immunosuppressants
3 L04A Immunosuppressants
4 L04AJ Complement inhibitors
5 L04AJ05

Active ingredients in L04AJ05

Active Ingredient Description
Avacopan

Avacopan is a selective antagonist of the human complement 5a receptor (C5aR1 or CD88) and competitively inhibits the interaction between C5aR1 and the anaphylatoxin C5a. The specific and selective blockade of C5aR1 by avacopan reduces the pro-inflammatory effects of C5a, which include neutrophil activation, migration, and adherence to sites of small blood vessel inflammation, vascular endothelial cell retraction and permeability.

Related product monographs

Title Information Source Document Type  
TAVNEOS Hard capsule European Medicines Agency (EU) MPI, EU: SmPC

Medicines in this ATC group

Estonia (EE)

Ireland (IE)

Israel (IL)

Japan (JP)

Poland (PL)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.