The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
L | Antineoplastic and immunomodulating agents | |
2
|
L04 | Immunosuppressants | |
3
|
L04A | Immunosuppressants | |
4
|
L04AG | Monoclonal antibodies | |
5
|
L04AG19 |
| Active Ingredient |
|---|
|
Axatilimab is a monoclonal antibody that binds to colony stimulating factor-1 receptors (CSF-1R) expressed on monocytes and macrophages. Blocking CSF-1R with axatilimab reduces the levels of these circulating proinflammatory and profibrotic monocytes and monocyte-derived macrophages, as demonstrated by a reduction of nonclassical monocyte counts in nonclinical studies with axatilimab, and inhibits the activity of pathogenic macrophages in tissues. |
| Document | Type | Information Source | |
|---|---|---|---|
| NIKTIMVO Solution for injection | MPI, US: SPL/PLR | FDA, National Drug Code (US) |