The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | L | Antineoplastic and immunomodulating agents | |
| 2 | L04 | Immunosuppressants | |
| 3 | L04A | Immunosuppressants | |
| 4 | L04AX | Other immunosuppressants | |
| 5 | L04AX07 |
| Active Ingredient | Description | |
|---|---|---|
| Dimethyl fumarate |
The anti-inflammatory and immunomodulating effects of dimethyl fumarate and its metabolite monomethyl fumarate are not fully elucidated but are thought to be mainly due to the interaction with the intracellular reduced glutathione of cells directly involved in the pathogenesis of psoriasis. Their main activity is considered to be immunomodulatory, resulting in a shift in T helper cells (Th) from the Th1 and Th17 profile to a Th2 phenotype. |
| Title | Information Source | Document Type | |
|---|---|---|---|
| DIMETHYL FUMARATE MYLAN Gastro-resistant hard capsule | European Medicines Agency (EU) | MPI, EU: SmPC | |
| SKILARENCE Gastro-resistant tablet | European Medicines Agency (EU) | MPI, EU: SmPC | |
| TECFIDERA Gastro-resistant hard capsule | European Medicines Agency (EU) | MPI, EU: SmPC |
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.
