The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | M | Musculo-skeletal system | |
| 2 | M04 | Antigout preparations | |
| 3 | M04A | Antigout preparations | |
| 4 | M04AB | Preparations increasing uric acid excretion | |
| 5 | M04AB05 |
| Active Ingredient | Description | |
|---|---|---|
| Lesinurad |
Lesinurad is a selective uric acid reabsorption inhibitor that inhibits uric acid transporter URAT1. URAT1 is responsible for the majority of the reabsorption of filtered uric acid from the renal tubular lumen. By inhibiting URAT1, lesinurad increases uric acid excretion and thereby lowers serum uric acid (sUA). Lesinurad also inhibits OAT4, a uric acid transporter involved in diuretic-induced hyperuricaemia. |
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.
