ATC Group: N05CJ Orexin receptor antagonists

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of N05CJ in the ATC hierarchy

Level Code Title
1 N Nervous system
2 N05 Psycholeptics
3 N05C Hypnotics and sedatives
4 N05CJ Orexin receptor antagonists

Group N05CJ contents

Code Title
N05CJ01
N05CJ02
N05CJ03

Active ingredients in N05CJ

Active Ingredient Description
Daridorexant

Daridorexant is a dual orexin receptor antagonist, acting on both orexin 1 and orexin 2 receptors and equipotent on both. The orexin neuropeptides (orexin A and orexin B) act on orexin receptors to promote wakefulness. Daridorexant antagonises the activation of orexin receptors by the orexin neuropeptides and consequently decreases the wake drive, allowing sleep to occur, without altering the proportion of sleep stages.

Suvorexant