ATC Group: R05DB29 Gefapixant

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of R05DB29 in the ATC hierarchy

Level Code Title
1 R Respiratory system
2 R05 Cough and cold preparations
3 R05D Cough suppressants, excl. combinations with expectorants
4 R05DB Other cough suppressants
5 R05DB29

Active ingredients in R05DB29

Active Ingredient Description
Gefapixant

Gefapixant is a selective antagonist of the P2X3 receptor. P2X3 receptors are ATP-gated ion channels found on sensory C fibres of the vagus nerve in the airways. C fibres are activated in response to inflammation or chemical irritants. Blockade of ATP signalling through P2X3 receptors reduces excessive sensory-nerve activation and excessive cough induced by extracellular ATP.

Related product monographs

Title Information Source Document Type  
LYFNUA Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

Medicines in this ATC group

Croatia (HR)

Estonia (EE)

Ireland (IE)

Italy (IT)

Japan (JP)

Lithuania (LT)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.