ATC Group: V03AC Iron chelating agents

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of V03AC in the ATC hierarchy

Level Code Title
1 V Various
2 V03 All other therapeutic products
3 V03A All other therapeutic products
4 V03AC Iron chelating agents

Group V03AC contents

Code Title
V03AC01 Deferoxamine
V03AC02 Deferiprone
V03AC03 Deferasirox

Active ingredients in V03AC

Active Ingredient Description
Deferasirox

Deferasirox is an orally active chelator that is highly selective for iron (III). It is a tridentate ligand that binds iron with high affinity in a 2:1 ratio. Deferasirox promotes excretion of iron, primarily in the faeces.

Deferiprone

Deferiprone is a bidentate ligand which binds iron in a 3:1 molar ratio. Deferiprone monotherapy is indicated for the treatment of iron overload in patients with thalassaemia major when current chelation therapy is contraindicated or inadequate.

Deferoxamine

Deferoxamine is a chelating agent for trivalent iron and aluminium ions. The resulting chelates are stable and non-toxic.

Related product monographs

Title Information Source Document Type  
DESFERAL Sterile, lyophilised powder Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
EXJADE Dispersible tablet European Medicines Agency (EU) MPI, EU: SmPC
EXJADE Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC
EXJADE Granules in sachet European Medicines Agency (EU) MPI, EU: SmPC
Ferriprox 100 mg/ml oral solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
FERRIPROX Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC
JADENU Film-coated tablet / Granules FDA, National Drug Code (US) MPI, US: SPL/PLR