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ABIRANAT

Found in: Singapore

Active Ingredients

#
Chemical substance
Description
1
Abiraterone

Abiraterone acetate is converted in vivo to abiraterone, an androgen biosynthesis inhibitor. Specifically, abiraterone selectively inhibits the enzyme 17α-hydroxylase/C17,20-lyase (CYP17). This enzyme is expressed in and is required for androgen biosynthesis in testicular, adrenal and prostatic tumour tissues. CYP17 inhibition also results in increased mineralocorticoid production by the adrenals.

ATC Classification

Code
Title
Category
L02BX03
Abiraterone
L Antineoplastic and immunomodulating agents → L02 Endocrine therapy → L02B Hormone antagonists and related agents → L02BX Other hormone antagonists and related agents

Identifiers

Authority
Identifier(s)
Health Sciences Authority (SG)
Identifier(s): 15833P