Abiraterone Other names: Abiraterone Acetate

Chemical formula: C₂₄H₃₁NO Molecular mass: 349.509 g/mol PubChem compound: 132971

Active ingredient description

Abiraterone acetate is converted in vivo to abiraterone, an androgen biosynthesis inhibitor. Specifically, abiraterone selectively inhibits the enzyme 17α-hydroxylase/C17,20-lyase (CYP17). This enzyme is expressed in and is required for androgen biosynthesis in testicular, adrenal and prostatic tumour tissues. CYP17 inhibition also results in increased mineralocorticoid production by the adrenals.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group		Classification
L02BX03	Abiraterone	L Antineoplastic and immunomodulating agents → L02 Endocrine therapy → L02B Hormone antagonists and related agents → L02BX Other hormone antagonists and related agents
Discover more medicines within L02BX03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document	Type	Information Source
ZYTIGA Film-coated tablet	MPI, EU: SmPC	Medicines & Healthcare Products Regulatory Agency (GB)
ZYTIGA Tablet	MPI, EU: SmPC	European Medicines Agency (EU)

Medicines

Abiraterone is an active ingredient of these brands:

Australia (AU)

ZYTIGA as ABIRATERONE ACETATE

Austria (AT)

ZYTIGA as ABIRATERONE ACETATE
(combination) AKEEGA as ABIRATERONE ACETATE

Brazil (BR)

BALEFIO as ABIRATERONE ACETATE
MATIZ as ABIRATERONE ACETATE
RARIJA as ABIRATERONE ACETATE
VENOMY as ABIRATERONE ACETATE
ZOSTIDE as ABIRATERONE ACETATE
ZYTIGA as ABIRATERONE ACETATE

Canada (CA)

ZYTIGA as ABIRATERONE ACETATE

Croatia (HR)

ZYTIGA as ABIRATERONE ACETATE
(combination) AKEEGA as ABIRATERONE ACETATE

Cyprus (CY)

ZYTIGA as ABIRATERONE ACETATE

Ecuador (EC)

ABIRATRAL as ABIRATERONE ACETATE
ABIRAVITAE as ABIRATERONE ACETATE
BIRATO as ABIRATERONE ACETATE
BITERA as ABIRATERONE ACETATE
KESTAVA as ABIRATERONE ACETATE
MATIZ as ABIRATERONE ACETATE
XATERON as ABIRATERONE ACETATE
ZYTIGA as ABIRATERONE ACETATE
ZYVALIX as ABIRATERONE ACETATE

Estonia (EE)

ZYTIGA as ABIRATERONE ACETATE

France (FR)

ZYTIGA as ABIRATERONE ACETATE
(combination) AKEEGA as ABIRATERONE ACETATE

Hong Kong (HK)

ABIRANAT as ABIRATERONE ACETATE
ZYTIGA as ABIRATERONE ACETATE

Ireland (IE)

ZYTIGA as ABIRATERONE ACETATE

Israel (IL)

ZYTIGA as ABIRATERONE ACETATE

Italy (IT)

ZYTIGA as ABIRATERONE ACETATE

Japan (JP)

ZYTIGA as ABIRATERONE ACETATE

Lithuania (LT)

TATICA as ABIRATERONE ACETATE
ZYTIGA as ABIRATERONE ACETATE
(combination) AKEEGA as ABIRATERONE ACETATE

Mexico (MX)

ZYTIGA as ABIRATERONE ACETATE

Netherlands (NL)

ZYTIGA as ABIRATERONE ACETATE

New Zealand (NZ)

YONSA as ABIRATERONE ACETATE
ZYTIGA as ABIRATERONE ACETATE

Nigeria (NG)

ZYTIGA as ABIRATERONE ACETATE

Poland (PL)

ABIRAL as ABIRATERONE ACETATE
GRUMABIX as ABIRATERONE ACETATE
TATICA as ABIRATERONE ACETATE
ZYTIGA as ABIRATERONE ACETATE

Romania (RO)

BIXODALAN
TATICA as ABIRATERONE ACETATE
ZYTIGA as ABIRATERONE ACETATE

Singapore (SG)

ABIRANAT as ABIRATERONE ACETATE
ZYTIGA as ABIRATERONE ACETATE

South Africa (ZA)

ABIKEM
ZYBERA
ZYTIGA as ABIRATERONE ACETATE

Spain (ES)

ZYTIGA as ABIRATERONE ACETATE

Tunisia (TN)

ZYTIGA as ABIRATERONE ACETATE

Turkey (TR)

ABETYL as ABIRATERONE ACETATE
ABIRATEX as ABIRATERONE ACETATE
ABITIGA as ABIRATERONE ACETATE
ABYGA as ABIRATERONE ACETATE
ARVILA as ABIRATERONE ACETATE
BYRETU as ABIRATERONE ACETATE
DIPON as ABIRATERONE ACETATE
RATEBIR as ABIRATERONE ACETATE
ZATERON as ABIRATERONE ACETATE
ZYTIGA as ABIRATERONE ACETATE

United Kingdom (UK)

ZYTIGA as ABIRATERONE ACETATE

United States (US)

YONSA as ABIRATERONE ACETATE
ZYTIGA as ABIRATERONE ACETATE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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