This brand name is authorized in Australia, Brazil, Canada, Ecuador, Hong Kong, Israel, Japan, New Zealand, Singapore, Tunisia, Turkey, United States, South Africa

Active ingredients

The drug ACTEMRA contains one active pharmaceutical ingredient (API):

1 Tocilizumab

Tocilizumab binds specifically to both soluble and membrane-bound IL-6 receptors (sIL-6R and mIL-6R). IL-6 is involved in diverse physiological processes such as T-cell activation, induction of immunoglobulin secretion, induction of hepatic acute phase protein synthesis and stimulation of haemopoiesis. IL-6 has been implicated in the pathogenesis of diseases including inflammatory diseases, osteoporosis and neoplasia.

Read about Tocilizumab

Medication package inserts

Below package inserts are available for further reading:

Title Information Source Document Type  
ACTEMRA Solution for injection FDA, National Drug Code (US) MPI, US: SPL/PLR

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
L04AC07 Tocilizumab L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AC Interleukin inhibitors
Discover more medicines within L04AC07

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: AU Pharmaceutical Benefits Scheme Identifier(s): 10056G, 10058J, 10060L, 10064Q, 10068X, 10071C, 10072D, 10073E, 10077J, 10078K, 10079L, 10081N, 10951J, 10954M, 11565Q, 11567T, 11720W, 11721X, 11722Y, 11725D, 11730J, 11734N, 11741Y, 11742B, 11743C, 11744D, 11748H, 11750K, 12083Y, 12084B, 12085C, 12086D, 12090H, 12094M, 12095N, 12099T, 12102Y, 12105D, 1419Q, 1423X, 1464C, 1476Q, 1481Y, 1482B, 9657G, 9658H, 9659J, 9671B, 9672C, 9673D
Country: BR Câmara de Regulação do Mercado de Medicamentos Identifier(s): 529208501150212, 529208502157210, 529215110026303, 529220090026707, 529220090026807
Country: CA Health Products and Food Branch Identifier(s): 02350092, 02350106, 02350114, 02424770, 02483327
Country: EC Agencia Nacional de Regulación, Control y Vigilancia Sanitaria Identifier(s): 202-MBE-0621, 28938-07-09
Country: HK Department of Health Drug Office Identifier(s): 59200, 59201, 59202, 63771
Country: IL מִשְׂרַד הַבְּרִיאוּת Identifier(s): 6415, 6416, 7772
Country: JP 医薬品医療機器総合機構 Identifier(s): 6399421A1020, 6399421A2026, 6399421A3022, 6399421G1022, 6399421G2029
Country: NZ Medicines and Medical Devices Safety Authority Identifier(s): 13435, 15812
Country: SG Health Sciences Authority Identifier(s): 13723P, 14837P
Country: TN Direction de la Pharmacie et du Médicament Identifier(s): 6993201H, 6993202H, 6993203H, 6993204H
Country: TR İlaç ve Tıbbi Cihaz Kurumu Identifier(s): 8699505762272, 8699505762289, 8699505762296, 8699505762302, 8699505762319, 8699505762326, 8699505952840
Country: US FDA, National Drug Code Identifier(s): 50242-135, 50242-136, 50242-137, 50242-138, 50242-143
Country: ZA Health Products Regulatory Authority Identifier(s): 43/30.1/0944, 43/30.1/0945, 43/30.1/0946, 49/30.1/0398

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