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ACTEMRA

Found in: Australia Canada Singapore United States

Active Ingredients

#
Chemical substance
Description
1
Tocilizumab

Tocilizumab binds specifically to both soluble and membrane-bound IL-6 receptors (sIL-6R and mIL-6R). IL-6 is involved in diverse physiological processes such as T-cell activation, induction of immunoglobulin secretion, induction of hepatic acute phase protein synthesis and stimulation of haemopoiesis. IL-6 has been implicated in the pathogenesis of diseases including inflammatory diseases, osteoporosis and neoplasia.

ATC Classification

Code
Title
Category
L04AC07
Tocilizumab
L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AC Interleukin inhibitors

Product Monographs

Monograph
Type
Country
ACTEMRA Solution for injection
MPI, US: SPL/PLR
US

Identifiers

Authority
Identifier(s)
FDA, National Drug Code (US)
Identifier(s): 50242-135, 50242-136, 50242-137, 50242-138, 50242-143
Health Products and Food Branch (CA)
Identifier(s): 02350092, 02350106, 02350114, 02424770, 02483327
Health Sciences Authority (SG)
Identifier(s): 13723P, 14837P
Pharmaceutical Benefits Scheme (AU)
Identifier(s): 10056G, 10058J, 10060L, 10064Q, 10068X, 10071C, 10072D, 10073E, 10077J, 10078K, 10079L, 10081N, 10951J, 10954M, 11565Q, 11567T, 11720W, 11721X, 11722Y, 11725D, 11730J, 11734N, 11741Y, 11742B, 11743C, 11744D, 11748H, 11750K, 12083Y, 12084B, 12085C, 12086D, 12090H, 12094M, 12095N, 12099T, 12102Y, 12105D, 1419Q, 1423X, 1464C, 1476Q, 1481Y, 1482B, 9657G, 9658H, 9659J, 9671B, 9672C, 9673D