ACTEMRA

Active ingredients

The drug ACTEMRA contains one active pharmaceutical ingredient (API):

UNII I031V2H011 - TOCILIZUMAB

Tocilizumab binds specifically to both soluble and membrane-bound IL-6 receptors (sIL-6R and mIL-6R). IL-6 is involved in diverse physiological processes such as T-cell activation, induction of immunoglobulin secretion, induction of hepatic acute phase protein synthesis and stimulation of haemopoiesis. IL-6 has been implicated in the pathogenesis of diseases including inflammatory diseases, osteoporosis and neoplasia.

Read about Tocilizumab

Medication package inserts

Below package inserts are available for further reading:

Title
Type
Country
Structured Product Labeling (SPL/PLR)
US

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code
Group title
Classification
Tocilizumab
L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AC Interleukin inhibitors
Discover more medicines within L04AC07

Authorization and marketing

This brand name is authorized in the following countries: Australia Brazil Canada Ecuador Hong Kong New Zealand Singapore Tunisia United States South Africa

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country
Identification scheme
Identifier(s)
AU
Pharmaceutical Benefits Scheme
Identifier(s): 10056G, 10058J, 10060L, 10064Q, 10068X, 10071C, 10072D, 10073E, 10077J, 10078K, 10079L, 10081N, 10951J, 10954M, 11565Q, 11567T, 11720W, 11721X, 11722Y, 11725D, 11730J, 11734N, 11741Y, 11742B, 11743C, 11744D, 11748H, 11750K, 12083Y, 12084B, 12085C, 12086D, 12090H, 12094M, 12095N, 12099T, 12102Y, 12105D, 1419Q, 1423X, 1464C, 1476Q, 1481Y, 1482B, 9657G, 9658H, 9659J, 9671B, 9672C, 9673D
BR
Câmara de Regulação do Mercado de Medicamentos
Identifier(s): 529208501150212, 529208502157210, 529215110026303, 529220090026707, 529220090026807
CA
Health Products and Food Branch
Identifier(s): 02350092, 02350106, 02350114, 02424770, 02483327
EC
Agencia Nacional de Regulación, Control y Vigilancia Sanitaria
Identifier(s): 202-MBE-0621, 28938-07-09
HK
Department of Health Drug Office
Identifier(s): 59200, 59201, 59202, 63771
NZ
Medicines and Medical Devices Safety Authority
Identifier(s): 13435, 15812
SG
Health Sciences Authority
Identifier(s): 13723P, 14837P
TN
Direction de la Pharmacie et du Médicament
Identifier(s): 6993201H, 6993202H, 6993203H, 6993204H
US
FDA, National Drug Code
Identifier(s): 50242-135, 50242-136, 50242-137, 50242-138, 50242-143
ZA
Health Products Regulatory Authority
Identifier(s): 43/30.1/0944, 43/30.1/0945, 43/30.1/0946, 49/30.1/0398