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Tocilizumab

Also known as: Atlizumab

Description

Tocilizumab binds specifically to both soluble and membrane-bound IL-6 receptors (sIL-6R and mIL-6R). IL-6 is involved in diverse physiological processes such as T-cell activation, induction of immunoglobulin secretion, induction of hepatic acute phase protein synthesis and stimulation of haemopoiesis. IL-6 has been implicated in the pathogenesis of diseases including inflammatory diseases, osteoporosis and neoplasia.

ATC Classification

Code
Title
Category
L04AC07
Tocilizumab
L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AC Interleukin inhibitors

Trade names

Trade name
Countries

Australia Canada Singapore United States

Austria Cyprus Netherlands

Product Monographs

Monograph
Type
Country
ACTEMRA Solution for injection
MPI, US: SPL/PLR
US
RoACTEMRA Concentrate for solution for infusion
MPI, EU: SmPC
RoACTEMRA Solution for injection in pre-filled syringe
MPI, EU: SmPC