ACTIFED DM COUGH

Brand name authorized in: Cyprus Singapore

Active ingredients

The drug ACTIFED DM COUGH contains a combination of these active pharmaceutical ingredients (APIs):

1 Triprolidine
UNII YAN7R5L890 - TRIPROLIDINE HYDROCHLORIDE
2 Pseudoephedrine
UNII 6V9V2RYJ8N - PSEUDOEPHEDRINE HYDROCHLORIDE

Pseudoephedrine is a sympathomimetic agent with direct and indirect effects on adrenergic receptors. It has alpha and beta adrenergic activity and some stimulant effect on the central nervous system. The sympathomimetic effect of pseudoephedrine produces vasoconstriction which in turn relieves nasal congestion.

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3 Demorphan
UNII 9D2RTI9KYH - DEXTROMETHORPHAN HYDROBROMIDE

Dextromethorphan is a non-opioid antitussive drug. The major metabolite of dextromethorphan, dextrorphan, binds with high affinity to σ-receptors to produce its antitussive activity without exhibiting the classic opiate effects that occur from binding into μ- and δ-receptors. In larger than therapeutic doses, dextrorphan is also an antagonist of N-methyl-D-aspartate (NMDA) receptors.

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Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code
Group title
Classification
Combinations
R Respiratory system → R05 Cough and cold preparations → R05D Cough suppressants, excl. combinations with expectorants → R05DA Opium alkaloids and derivatives
Discover more medicines within R05DA20

Unique identifiers

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country
Identification scheme
Identifier(s)
SG
Health Sciences Authority
Identifier(s): 03134P