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AKYNZEO

Found in: Austria Australia Canada Spain France Netherlands Singapore United Kingdom United States

Active Ingredients

#
Chemical substance
Description
1
Netupitant

Netupitant is a selective antagonist of human substance P/neurokinin 1 (NK1) receptors. Delayed emesis has been associated with the activation of tachykinin family neurokinin 1 (NK1) receptors (broadly distributed in the central and peripheral nervous systems) by substance P. As shown in in vitro and in vivo studies, netupitant inhibits substance P mediated responses.

2
Palonosetron

Palonosetron is a selective high-affinity receptor antagonist of the 5HT3 receptor.

ATC Classification

Code
Title
Category
A04AA55
Palonosetron, combinations
A Alimentary tract and metabolism → A04 Antiemetics and antinauseants → A04A Antiemetics and antinauseants → A04AA Serotonin (5HT3) antagonists

Identifiers

Authority
Identifier(s)
FDA, National Drug Code (US)
Identifier(s): 69639-101, 69639-102, 69639-105
Health Products and Food Branch (CA)
Identifier(s): 02468735
Health Sciences Authority (SG)
Identifier(s): 15031P
Pharmaceutical Benefits Scheme (AU)
Identifier(s): 10714X, 10731T
Z-Index G-Standaard PRK (NL)
Identifier(s): 139696
Base de données publique des médicaments (FR)
Identifier(s): 67693946
Centro de información online de medicamentos de la AEMPS (ES)
Identifier(s): 1151001001