Palonosetron

Chemical formula: C₁₉H₂₄N₂O  Molecular mass: 296.414 g/mol  PubChem compound: 6337614

Active ingredient description

Palonosetron is a selective high-affinity receptor antagonist of the 5HT3 receptor.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A04AA05 Palonosetron A Alimentary tract and metabolism → A04 Antiemetics and antinauseants → A04A Antiemetics and antinauseants → A04AA Serotonin (5HT3) antagonists
Discover more medicines within A04AA05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ALOXI Solution for injection European Medicines Agency (EU) MPI, EU: SmPC
ALOXI Soft capsule European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 135729-56-5
DrugBank Drug: DB00377
KEGG Drug: D07175
PubChem Compound: 6337614
RxNorm Ingredient: 70561
SNOMED-CT Concept: 404852008
Palonosetron (substance)
UNII Identifier: 5D06587D6R
PALONOSETRON

Medicines

Palonosetron is an active ingredient of these brands:

United States (US)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Australia (AU)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Austria (AT)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Brazil (BR)

  • ONICIT as PALONOSETRON HYDROCHLORIDE
  • PALOCYT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Canada (CA)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Croatia (HR)

  • FERANT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Cyprus (CY)

Ecuador (EC)

  • PALOHALT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Estonia (EE)

  • ALOXI as PALONOSETRON HYDROCHLORIDE
  • FERANT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Finland (FI)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

France (FR)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Hong Kong (HK)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Ireland (IE)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Israel (IL)

  • PALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Japan (JP)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

Lithuania (LT)

  • ALOXI as PALONOSETRON HYDROCHLORIDE
  • FERANT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Malta (MT)

  • FERANT as PALONOSETRON HYDROCHLORIDE

Mexico (MX)

  • ONICIT as PALONOSETRON HYDROCHLORIDE

Netherlands (NL)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

New Zealand (NZ)

  • ALOXI as PALONOSETRON HYDROCHLORIDE
  • ONICIT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Poland (PL)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Romania (RO)

  • ALOXI as PALONOSETRON HYDROCHLORIDE
  • FERANT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Singapore (SG)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

South Africa (ZA)

  • BEVATIVA as PALONOSETRON HYDROCHLORIDE
  • NOCIPAL as PALONOSETRON HYDROCHLORIDE
  • ONICIT as PALONOSETRON HYDROCHLORIDE
  • PALCITA as PALONOSETRON HYDROCHLORIDE
  • PALTON as PALONOSETRON HYDROCHLORIDE

Spain (ES)

  • ALOXI as PALONOSETRON HYDROCHLORIDE
  • FERANT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Tunisia (TN)

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Turkey (TR)

  • ALOXI as PALONOSETRON HYDROCHLORIDE
  • CINVEX as PALONOSETRON HYDROCHLORIDE
  • DEKOL
  • EMTRON as PALONOSETRON HYDROCHLORIDE
  • GENOLAX as PALONOSETRON HYDROCHLORIDE
  • LOTISA as PALONOSETRON HYDROCHLORIDE
  • PALODIN as PALONOSETRON HYDROCHLORIDE
  • PALOJECT as PALONOSETRON HYDROCHLORIDE
  • PALONDEM as PALONOSETRON HYDROCHLORIDE
  • PALONEX as PALONOSETRON HYDROCHLORIDE
  • PALOXITRON as PALONOSETRON HYDROCHLORIDE
  • PALSEL as PALONOSETRON HYDROCHLORIDE
  • PELATOS as PALONOSETRON HYDROCHLORIDE
  • PLARON as PALONOSETRON HYDROCHLORIDE
  • VOMISET as PALONOSETRON HYDROCHLORIDE
  • VONAXI as PALONOSETRON HYDROCHLORIDE
  • VOTRON as PALONOSETRON HYDROCHLORIDE
  • ZIAXE as PALONOSETRON HYDROCHLORIDE

United Kingdom (UK)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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