ALKAFIZZ

This brand name is authorized in South Africa

Active ingredients

The drug ALKAFIZZ contains a combination of these active pharmaceutical ingredients (APIs):

1 Citric acid
UNII 2968PHW8QP - CITRIC ACID MONOHYDRATE

Potassium citrate is indicated for the management of renal tubular acidosis with calcium stones, hypocitraturic calcium oxalate nephrolithiasis of any etiology, uric acid lithiasis with or without calcium stones. When potassium citrate is given orally, the metabolism of absorbed citrate produces an alkaline load. The induced alkaline load in turn increases urinary pH and raises urinary citrate by augmenting citrate clearance without measurably altering ultrafilterable serum citrate. Thus, potassium citrate therapy appears to increase urinary citrate principally by modifying the renal handling of citrate, rather than by increasing the filtered load of citrate.

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2 Sodium bicarbonate
UNII 8MDF5V39QO - SODIUM BICARBONATE

Sodium bicarbonate has antacid properties. Sodium bicarbonate causes neutralisation of gastric acid with the production of carbon dioxide.

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3 Sodium citrate
UNII 1Q73Q2JULR - SODIUM CITRATE, UNSPECIFIED FORM

Sodium citrate has no relevant pharmacodynamic activity other than that caused by its alkalinity (e.g. its gastric acid neutralising capacity). Sodium citrate is a non-particulate antacid for use by mouth to prior to general anaesthesia for caesarean section.

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4 Tartaric acid
UNII W4888I119H - TARTARIC ACID
Read about Tartaric acid

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: ZA Health Products Regulatory Authority Identifier(s): 29/18.3/0378, 31/18.3/0283

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