Citric acid

Chemical formula: C₆H₈O₇  Molecular mass: 192.124 g/mol  PubChem compound: 311

Active ingredient description

Potassium citrate is indicated for the management of renal tubular acidosis with calcium stones, hypocitraturic calcium oxalate nephrolithiasis of any etiology, uric acid lithiasis with or without calcium stones. When potassium citrate is given orally, the metabolism of absorbed citrate produces an alkaline load. The induced alkaline load in turn increases urinary pH and raises urinary citrate by augmenting citrate clearance without measurably altering ultrafilterable serum citrate. Thus, potassium citrate therapy appears to increase urinary citrate principally by modifying the renal handling of citrate, rather than by increasing the filtered load of citrate.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A09AB04 Citric acid A Alimentary tract and metabolism → A09 Digestives, incl. enzymes → A09A Digestives, incl. enzymes → A09AB Acid preparations
Discover more medicines within A09AB04

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 77-92-9
DrugBank Drug: DB04272
KEGG Drug: D00037
PubChem Compound: 311
RxNorm Ingredient: 21183
SNOMED-CT Concept: 75399008
Citric acid (substance)
UNII Identifier: XF417D3PSL

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