DIOCALM

This brand name is authorized in United Kingdom

Active ingredients

The drug DIOCALM contains a combination of these active pharmaceutical ingredients (APIs):

1 Citric acid
UNII XF417D3PSL - ANHYDROUS CITRIC ACID

Potassium citrate is indicated for the management of renal tubular acidosis with calcium stones, hypocitraturic calcium oxalate nephrolithiasis of any etiology, uric acid lithiasis with or without calcium stones. When potassium citrate is given orally, the metabolism of absorbed citrate produces an alkaline load. The induced alkaline load in turn increases urinary pH and raises urinary citrate by augmenting citrate clearance without measurably altering ultrafilterable serum citrate. Thus, potassium citrate therapy appears to increase urinary citrate principally by modifying the renal handling of citrate, rather than by increasing the filtered load of citrate.

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2 Glucose
UNII LX22YL083G - DEXTROSE MONOHYDRATE

Glucose is frequently used in both adults and children to restore blood glucose concentrations in the treatment of hypoglycaemia resulting from insulin excess or from other causes. The metabolism of glucose is an energy source for the body.

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3 Potassium chloride
UNII 660YQ98I10 - POTASSIUM CHLORIDE

Potassium plays a vital physiological role in maintenance of normal electrical excitability of nerve and muscle. It is also important in the genesis and correction of imbalances of acid-base metabolism.

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4 Sodium chloride
UNII 451W47IQ8X - SODIUM CHLORIDE

Sodium chloride is the principle salt involved in maintaining the osmotic tension of blood and tissues. Changes in osmotic tension influence the movement of fluids and diffusion of salts in cellular tissue.

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5 Sodium citrate
UNII 1Q73Q2JULR - SODIUM CITRATE, UNSPECIFIED FORM

Sodium citrate has no relevant pharmacodynamic activity other than that caused by its alkalinity (e.g. its gastric acid neutralising capacity). Sodium citrate is a non-particulate antacid for use by mouth to prior to general anaesthesia for caesarean section.

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Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: GB Medicines & Healthcare Products Regulatory Agency Identifier(s): 52020

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