XIMEPEG

This brand name is authorized in France

Active ingredients

The drug XIMEPEG contains a combination of these active pharmaceutical ingredients (APIs):

1 Macrogol
UNII 4R4HFI6D95 - POLYETHYLENE GLYCOL 4000

High molecular weight (4000) macrogols are long linear polymers which retain water molecules by means of hydrogen bonds. When administered by the oral route, they lead to an increase in volume of intestinal fluids.

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2 Sodium sulfate
UNII 36KCS0R750 - SODIUM SULFATE ANHYDROUS

Sodium Sulfate Anhydrous is the anhydrous, sodium salt form of sulfuric acid. Sodium sulfate anhydrous disassociates in water to provide sodium ions and sulfate ions. Sodium ion is the principal cation of the extracellular fluid and plays a large part in the therapy of fluid and electrolyte disturbances. Sodium sulfate anhydrous is an electrolyte replenisher and is used in isosmotic solutions so that administration does not disturb normal electrolyte balance and does not lead to absorption or excretion of water and ions.

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3 Simethicone
UNII 92RU3N3Y1O - DIMETHICONE

Simethicone is a chemically inert, non-systemic gastric defoaming agent that works by altering the elasticity of interfaces of mucus-embedded bubbles in the gastrointestinal tract. The gas bubbles are thus broken down or coalesced and in this form gas is more easily eliminated through eructation or passing flatus.

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4 Sodium citrate
UNII 1Q73Q2JULR - SODIUM CITRATE, UNSPECIFIED FORM

Sodium citrate has no relevant pharmacodynamic activity other than that caused by its alkalinity (e.g. its gastric acid neutralising capacity). Sodium citrate is a non-particulate antacid for use by mouth to prior to general anaesthesia for caesarean section.

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5 Citric acid
UNII 2968PHW8QP - CITRIC ACID MONOHYDRATE

Potassium citrate is indicated for the management of renal tubular acidosis with calcium stones, hypocitraturic calcium oxalate nephrolithiasis of any etiology, uric acid lithiasis with or without calcium stones. When potassium citrate is given orally, the metabolism of absorbed citrate produces an alkaline load. The induced alkaline load in turn increases urinary pH and raises urinary citrate by augmenting citrate clearance without measurably altering ultrafilterable serum citrate. Thus, potassium citrate therapy appears to increase urinary citrate principally by modifying the renal handling of citrate, rather than by increasing the filtered load of citrate.

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6 Sodium chloride
UNII 451W47IQ8X - SODIUM CHLORIDE

Sodium chloride is the principle salt involved in maintaining the osmotic tension of blood and tissues. Changes in osmotic tension influence the movement of fluids and diffusion of salts in cellular tissue.

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7 Potassium chloride
UNII 660YQ98I10 - POTASSIUM CHLORIDE

Potassium plays a vital physiological role in maintenance of normal electrical excitability of nerve and muscle. It is also important in the genesis and correction of imbalances of acid-base metabolism.

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Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
A06AD65 Macrogol, combinations A Alimentary tract and metabolism → A06 Laxatives → A06A Laxatives → A06AD Osmotically acting laxatives
Discover more medicines within A06AD65

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: FR Base de donnรฉes publique des mรฉdicaments Identifier(s): 62090079

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