CIBADREX

This brand name is authorized in Germany, France, Italy, Turkey, South Africa

Active ingredients

The drug CIBADREX contains a combination of these active pharmaceutical ingredients (APIs):

1 Benazepril
UNII N1SN99T69T - BENAZEPRIL HYDROCHLORIDE

Benazepril is a prodrug which, after hydrolysis to the active substance benazeprilat, inhibits the angiotensin-converting enzyme (ACE) and so blocks the conversion of angiotensin I to angiotensin II. This reduces all the effects mediated by angiotensin II – i.e. vasoconstriction and production of aldosterone, which promotes the reabsorption of sodium and water in the renal tubules – and elevates cardiac output.

Read about Benazepril
2 Hydrochlorothiazide
UNII 0J48LPH2TH - HYDROCHLOROTHIAZIDE

Hydrochlorothiazide is a diuretic with antihypertensive properties. It acts by inhibiting the renal tubular re-absorption of sodium and chloride ions, which are excreted with an accompanying volume of water. Potassium excretion is also promoted.

Read about Hydrochlorothiazide

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
C09AA07 Benazepril C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09A ACE inhibitors, plain → C09AA ACE inhibitors, plain
Discover more medicines within C09AA07
C09BA07 Benazepril and diuretics C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09B ACE inhibitors, combinations → C09BA ACE inhibitors and diuretics
Discover more medicines within C09BA07

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: DE Bundesinstitut für Arzneimittel und Medizinprodukte Identifier(s): 04855477
Country: FR Base de données publique des médicaments Identifier(s): 61591226
Country: IT Agenzia del Farmaco Identifier(s): 028037024
Country: TR İlaç ve Tıbbi Cihaz Kurumu Identifier(s): 8698856090072, 8698856090089
Country: ZA Health Products Regulatory Authority Identifier(s): 28/7.1.3/0120, 28/7.1.3/0121, 28/7.1.3/0122, 28/7.1.3/0123

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