DUOLIN

This brand name is authorized in Ecuador, New Zealand, South Africa

Active ingredients

The drug DUOLIN contains a combination of these active pharmaceutical ingredients (APIs):

1 Ipratropium
UNII J697UZ2A9J - IPRATROPIUM BROMIDE

Ipratropium is a quaternary ammonium compound with anticholinergic (parasympatholytic) properties. Ipratropium appears to inhibit vagally mediated reflexes by antagonising the action of acetylcholine, the transmitter agent released from the vagus nerve. Anticholinergics prevent the increase in intracellular concentration of Ca++, which is caused by interaction of acetylcholine with the muscarinic receptor on bronchial smooth muscle. Ca++ release is mediated by the second messenger system consisting of IP3 (inositol triphosphate) and DAG (diacylglycerol).

Read about Ipratropium
2 Salbutamol
UNII 021SEF3731 - ALBUTEROL SULFATE

Salbutamol is a selective ฮฒ2-agonist providing short-acting (4-6 hour) bronchodilation with a fast onset (within 5 minutes) in reversible airways obstruction. At therapeutic doses it acts on the ฮฒ2-adrenoceptors of bronchial muscle. Salbutamol is administered for the symptomatic relief of bronchospasm associated with chronic or acute asthma, bronchitis or other obstructive pulmonary diseases.

Read about Salbutamol

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
R03AL02 Salbutamol and ipratropium bromide R Respiratory system → R03 Drugs for obstructive airway diseases → R03A Adrenergics, inhalants → R03AL Adrenergics in combination with anticholinergics
Discover more medicines within R03AL02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: EC Agencia Nacional de Regulaciรณn, Control y Vigilancia Sanitaria Identifier(s): 29742-04-11
Country: NZ Medicines and Medical Devices Safety Authority Identifier(s): 10326, 12778
Country: ZA Health Products Regulatory Authority Identifier(s): 37/10.2.1/0012, 41/10.2.1/0908

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