This brand name is authorized in Brazil, Singapore, South Africa
The drug DUOVENT contains a combination of these active pharmaceutical ingredients (APIs):
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1
Fenoterol
UNII RLI45Z99RB - FENOTEROL HYDROBROMIDE
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2
Ipratropium bromide monohydrate
UNII J697UZ2A9J - IPRATROPIUM BROMIDE
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Ipratropium is a quaternary ammonium compound with anticholinergic (parasympatholytic) properties. Ipratropium appears to inhibit vagally mediated reflexes by antagonising the action of acetylcholine, the transmitter agent released from the vagus nerve. Anticholinergics prevent the increase in intracellular concentration of Ca++, which is caused by interaction of acetylcholine with the muscarinic receptor on bronchial smooth muscle. Ca++ release is mediated by the second messenger system consisting of IP3 (inositol triphosphate) and DAG (diacylglycerol). |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| DUOVENT UDV Nebulizer solution | Marketing Authorisation Holder | MPI, CA: SPM |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| R03AL01 | R Respiratory system → R03 Drugs for obstructive airway diseases → R03A Adrenergics, inhalants → R03AL Adrenergics in combination with anticholinergics | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: BR | Câmara de Regulação do Mercado de Medicamentos | Identifier(s): 504505701175314 |
| Country: SG | Health Sciences Authority | Identifier(s): 07913P |
| Country: ZA | Health Products Regulatory Authority | Identifier(s): 35/10.2.1/0302 |
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