DYAZIDE

This brand name is authorized in United Kingdom, United States, South Africa

Active ingredients

The drug DYAZIDE contains a combination of these active pharmaceutical ingredients (APIs):

1 Hydrochlorothiazide
UNII 0J48LPH2TH - HYDROCHLOROTHIAZIDE

Hydrochlorothiazide is a diuretic with antihypertensive properties. It acts by inhibiting the renal tubular re-absorption of sodium and chloride ions, which are excreted with an accompanying volume of water. Potassium excretion is also promoted.

Read about Hydrochlorothiazide
2 Triamterene
UNII WS821Z52LQ - TRIAMTERENE

Triamterene is a potassium-sparing agent. Triamterene inhibits the reabsorption of sodium ions in exchange for potassium and hydrogen ions at that segment of the distal tubule under the control of adrenal mineralocorticoids (especially aldosterone). The fraction of filtered sodium reaching this distal tubular exchange site is relatively small, and the amount which is exchanged depends on the level of mineralocorticoid activity. Thus, the degree of natriuresis and diuresis produced by inhibition of the exchange mechanism is necessarily limited.

Read about Triamterene

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
C03EA01 Hydrochlorothiazide and potassium-sparing agents C Cardiovascular system → C03 Diuretics → C03E Diuretics and potassium-sparing agents in combination → C03EA Low-ceiling diuretics and potassium-sparing agents
Discover more medicines within C03EA01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: GB Medicines & Healthcare Products Regulatory Agency Identifier(s): 18838
Country: US FDA, National Drug Code Identifier(s): 0007-3650
Country: ZA Health Products Regulatory Authority Identifier(s): G/18.1/71

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