Brand name authorized in: Italy Singapore South Africa

Active ingredients

The drug EXINEF contains one active pharmaceutical ingredient (API):

1 Etoricoxib

Etoricoxib is an oral, selective cyclo-oxygenase-2 (COX-2) inhibitor within the clinical dose range. Cyclooxygenase is responsible for generation of prostaglandins. Two isoforms, COX-1 and COX-2, have been identified. COX-2 is the isoform of the enzyme that has been shown to be induced by pro-inflammatory stimuli and has been postulated to be primarily responsible for the synthesis of prostanoid mediators of pain, inflammation, and fever. COX-2 is also involved in ovulation, implantation and closure of the ductus arteriosus, regulation of renal function, and central nervous system functions (fever induction, pain perception and cognitive function). It may also play a role in ulcer healing. COX-2 has been identified in tissue around gastric ulcers in man but its relevance to ulcer healing has not been established.

Read about Etoricoxib

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code
Group title
M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AH Coxibs
Discover more medicines within M01AH05

Unique identifiers

This drug has been assigned below unique identifiers within the countries it is being marketed:

Identification scheme
Agenzia Italiana del Farmaco
Identifier(s): 035822067, 035822206, 035822307
Health Sciences Authority
Identifier(s): 14943P, 14944P, 14945P
Health Products Regulatory Authority
Identifier(s): 44/3.1/0898, 44/3.1/0899, 44/3.1/0900, 44/3.1/0901