INSPIOLTO RESPIMAT

This brand name is authorized in Canada, Finland

Active ingredients

The drug INSPIOLTO RESPIMAT contains a combination of these active pharmaceutical ingredients (APIs):

1 Tiotropium
UNII L64SXO195N - TIOTROPIUM BROMIDE MONOHYDRATE

Tiotropium is a long-acting, specific, muscarinic receptor antagonist, in clinical medicine often called an anticholinergic. By binding to the muscarinic receptors in the bronchial smooth musculature, tiotropium inhibits the cholinergic (bronchoconstrictive) effects of acetylcholine, released from parasympathetic nerve endings.

Read about Tiotropium
2 Olodaterol
UNII 65R445W3V9 - OLODATEROL HYDROCHLORIDE

Olodaterol has a high affinity and high selectivity to the human beta2-adrenoceptor. The compound exerts its pharmacological effects by binding and activation of beta2-adrenoceptors after topical administration by inhalation. Activation of these receptors in the airways results in a stimulation of intracellular adenyl cyclase, an enzyme that mediates the synthesis of cyclic-3',5' adenosine monophosphate (cAMP). Elevated levels of cAMP induce bronchodilation by relaxation of airway smooth muscle cells.

Read about Olodaterol

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
R03AL06 Olodaterol and tiotropium bromide R Respiratory system → R03 Drugs for obstructive airway diseases → R03A Adrenergics, inhalants → R03AL Adrenergics in combination with anticholinergics
Discover more medicines within R03AL06

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: CA Health Products and Food Branch Identifier(s): 02441888
Country: FI Lรครคkealan turvallisuus- ja kehittรคmiskeskus Identifier(s): 062119, 151061, 461158, 579248

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