Chemical formula: C₁₉H₂₂NO₄S₂ Molecular mass: 392.512 g/mol PubChem compound: 5487427
Tiotropium is a long-acting, specific, muscarinic receptor antagonist, in clinical medicine often called an anticholinergic. By binding to the muscarinic receptors in the bronchial smooth musculature, tiotropium inhibits the cholinergic (bronchoconstrictive) effects of acetylcholine, released from parasympathetic nerve endings.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| R03BB04 | Tiotropium bromide | R Respiratory system → R03 Drugs for obstructive airway diseases → R03B Other drugs for obstructive airway diseases, inhalants → R03BB Anticholinergics |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| SPIRIVA Inhalation powder, hard capsule | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| SPIRIVA RESPIMAT Inhalation solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Tiotropium is an active ingredient of these brands:
United States (US)
Australia (AU)Austria (AT)Brazil (BR)Canada (CA)
Croatia (HR)Cyprus (CY)Ecuador (EC)
Estonia (EE)Finland (FI)France (FR)Hong Kong (HK)Ireland (IE)Israel (IL)Japan (JP)Lithuania (LT)
Malta (MT)Mexico (MX)
Netherlands (NL)New Zealand (NZ)Poland (PL)
Romania (RO)Singapore (SG)Spain (ES)Tunisia (TN)Turkey (TR)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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