ISOVORIN

This brand name is authorized in Spain, Japan, United Kingdom

Active ingredients

The drug ISOVORIN contains one active pharmaceutical ingredient (API):

1 Levofolinic acid UNII 990S25980Y - LEVOLEUCOVORIN

Levoleucovorin is the pharmacologically active isomer of 5-formyltetrahydrofolic acid. Administration of levoleucovorin can “rescue” normal cells and thereby prevent toxicity of folic acid antagonists such as methotrexate which act by inhibiting dihydrofolate reductase. Read about Levoleucovorin

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
ISOVORIN Solution for injection	Medicines & Healthcare Products Regulatory Agency (GB)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
V03AF04	Calcium levofolinate	V Various → V03 All other therapeutic products → V03A All other therapeutic products → V03AF Detoxifying agents for antineoplastic treatment
Discover more medicines within V03AF04

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 60866, 61291, 61292
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 101322, 46331
Country: JP	医薬品医療機器総合機構	Identifier(s): 3929407D1160, 3929407D2108