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Calcium levofolinate

Also known as: Levofolinic acid Leucovorin calcium

Description

Levofolinate is the pharmacologically active isomer of 5-formyltetrahydrofolic acid. Administration of levofolinate can “rescue” normal cells and thereby prevent toxicity of folic acid antagonists such as methotrexate which act by inhibiting dihydrofolate reductase.

ATC Classification

Code
Title
Category
V03AF04
Calcium levofolinate
V Various → V03 All other therapeutic products → V03A All other therapeutic products → V03AF Detoxifying agents for antineoplastic treatment

Trade names

Trade name
Countries

France

United States

Product Monographs

Monograph
Type
Country
LEVOFOLINIC ACID Solution for injection/infusion
MPI, EU: SmPC
UK
ISOVORIN Solution for injection
MPI, EU: SmPC
UK