This brand name is authorized in United States.
The drug LYNAVOY contains one active pharmaceutical ingredient (API):
1
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UNII
386012Z45S - LINERIXIBAT
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Linerixibat is a reversible inhibitor of the ileal bile acid transporter (IBAT). It decreases the reabsorption of bile acids in the terminal ileum leading to their increased fecal elimination. Cholestatic pruritus is a common symptom in patients with PBC, and the pathophysiology of pruritus in patients with PBC is not completely understood. Although the complete mechanism by which linerixibat improves pruritus in PBC patients is unknown, it may involve inhibition of the IBAT as observed by a decrease in mediators of pruritus including serum bile acids. |
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Below package inserts are available for further reading:
| Document | Type | Information Source | |
|---|---|---|---|
| LYNAVOY Film-coated tablet | MPI, US: SPL/PLR | FDA, National Drug Code (US) |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| US | FDA, National Drug Code | 0173-0938 |
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